CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris

Engagement of the B7 family of molecules on antigen-presenting cells with their T cell–associated ligands, CD28 and CD152 (cytotoxic T lymphocyte–associated antigen-4 [CTLA-4]), provides a pivotal costimulatory signal in T-cell activation. We investigated the role of the CD28/CD152 pathway in psoria...

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書誌詳細

出版年:	J Clin Invest
主要な著者:	Abrams, Judith R., Lebwohl, Mark G., Guzzo, Cynthia A., Jegasothy, Brian V., Goldfarb, Michael T., Goffe, Bernard S., Menter, Alan, Lowe, Nicholas J., Krueger, Gerald, Brown, Michael J., Weiner, Russell S., Birkhofer, Martin J., Warner, Garvin L., Berry, Karen K., Linsley, Peter S., Krueger, James G., Ochs, Hans D., Kelley, Susan L., Kang, Sewon
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Clinical Investigation 1999
主題:	Article
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC408469/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10225967/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI5857
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