Interleukin-10 (IL-10) in Experimental Visceral Leishmaniasis and IL-10 Receptor Blockade as Immunotherapy

Interleukin-10 (IL-10) is thought to promote intracellular infection, including human visceral leishmaniasis, by disabling Th1 cell-type responses and/or deactivating parasitized tissue macrophages. To develop a rationale for IL-10 inhibition as treatment in visceral infection, Th1 cytokine-driven r...

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Detalhes bibliográficos
Main Authors: Murray, Henry W., Lu, Christina M., Mauze, Smita, Freeman, Sherry, Moreira, Andre L., Kaplan, Gilla, Coffman, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC130311/
https://ncbi.nlm.nih.gov/pubmed/12379707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.11.6284-6293.2002
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