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Interleukin-10 (IL-10) in Experimental Visceral Leishmaniasis and IL-10 Receptor Blockade as Immunotherapy

Interleukin-10 (IL-10) is thought to promote intracellular infection, including human visceral leishmaniasis, by disabling Th1 cell-type responses and/or deactivating parasitized tissue macrophages. To develop a rationale for IL-10 inhibition as treatment in visceral infection, Th1 cytokine-driven r...

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Podrobná bibliografie
Vydáno v:Infect Immun
Hlavní autoři: Murray, Henry W., Lu, Christina M., Mauze, Smita, Freeman, Sherry, Moreira, Andre L., Kaplan, Gilla, Coffman, Robert L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC130311/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12379707/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.11.6284-6293.2002
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