Impact of the functional status of saeRS on in vivo phenotypes of Staphylococcus aureus sarA mutants

We investigated the in vivo relevance of the impact of sarA and saeRS on protease production using derivatives of the USA300 strain LAC. The results confirmed that mutation of saeRS or sarA reduces virulence in a bacteremia model to a comparable degree. However, while eliminating protease production...

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Main Authors: Beenken, Karen E., Mrak, Lara N., Zielinska, Agnieszka K., Atwood, Danielle N., Loughran, Allister J., Griffin, Linda M., Matthews, K. Alice, Anthony, Allison M., Spencer, Horace J., Post, Ginell R., Lee, Chia Y., Smeltzer, Mark S.
格式: Artigo
語言:Inglês
出版: 2014
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084611/
https://ncbi.nlm.nih.gov/pubmed/24779437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12629
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