sarA-mediated repression of protease production plays a key role in the pathogenesis of Staphylococcus aureus USA300 isolates

Mutation of staphylococcal accessory regulator (sarA) results in increased production of extracellular proteases in Staphylococcus aureus, which has been correlated with decreased biofilm formation and decreased accumulation of extracellular toxins. We used murine models of implant-associated biofil...

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Autori principali: Zielinska, Agnieszka K., Beenken, Karen E., Mrak, Lara N, Spencer, Horace J., Post, Ginell R., Skinner, Robert A., Tackett, Alan J., Horswill, Alexander R., Smeltzer, Mark S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508076/
https://ncbi.nlm.nih.gov/pubmed/23075270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12048
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