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The ability of sarA to limit protease production plays a key role in the pathogenesis of Staphylococcus aureus osteomyelitis irrespective of the functional status of agr

ABSTRACT We demonstrate that mutation of the staphylococcal accessory regulator A (sarA) in the USA300 strain LAC limits virulence in a murine osteomyelitis model to a greater extent than mutation of the accessory gene regulator (agr) and that it does so irrespective of the functional status of agr....

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Principais autores: Karen E. Beenken, Mara J. Campbell, Mark S. Smeltzer
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2025-01-01
叢編:Infection and Immunity
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在線閱讀:https://journals.asm.org/doi/10.1128/iai.00473-24
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