Impact of individual extracellular proteases on Staphylococcus aureus biofilm formation in diverse clinical isolates and their isogenic sarA mutants

We demonstrate that the purified Staphylococcus aureus extracellular proteases aureolysin, ScpA, SspA, and SspB limit biofilm formation, with aureolysin having the greatest impact. Using protease-deficient derivatives of LAC, we confirmed that this is due to the individual proteases themselves. Puri...

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Vydáno v:Microbiologyopen
Hlavní autoři: Loughran, Allister J, Atwood, Danielle N, Anthony, Allison C, Harik, Nada S, Spencer, Horace J, Beenken, Karen E, Smeltzer, Mark S
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2014
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263513/
https://ncbi.nlm.nih.gov/pubmed/25257373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.214
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