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Impact of individual extracellular proteases on Staphylococcus aureus biofilm formation in diverse clinical isolates and their isogenic sarA mutants

We demonstrate that the purified Staphylococcus aureus extracellular proteases aureolysin, ScpA, SspA, and SspB limit biofilm formation, with aureolysin having the greatest impact. Using protease-deficient derivatives of LAC, we confirmed that this is due to the individual proteases themselves. Puri...

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Dades bibliogràfiques
Publicat a:Microbiologyopen
Autors principals: Loughran, Allister J, Atwood, Danielle N, Anthony, Allison C, Harik, Nada S, Spencer, Horace J, Beenken, Karen E, Smeltzer, Mark S
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263513/
https://ncbi.nlm.nih.gov/pubmed/25257373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.214
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