Exploiting Correlations between Protein Abundance and the Functional Status of saeRS and sarA To Identify Virulence Factors of Potential Importance in the Pathogenesis of Staphylococcus aureus Osteomyelitis

[Image: see text] We used a murine model of postsurgical osteomyelitis (OM) to evaluate the relative virulence of the Staphylococcus aureus strain LAC and five isogenic variants that differ in the functional status of saeRS and sarA relative to each other. LAC and a variant in which saeRS activity i...

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Publicat a:ACS Infect Dis
Autors principals: Ramirez, Aura M., Byrum, Stephanie D., Beenken, Karen E., Washam, Charity, Edmondson, Rick D., Mackintosh, Samuel G., Spencer, Horace J., Tackett, Alan J., Smeltzer, Mark S.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2019
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294808/
https://ncbi.nlm.nih.gov/pubmed/31722523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.9b00291
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