Exploiting Correlations between Protein Abundance and the Functional Status of saeRS and sarA To Identify Virulence Factors of Potential Importance in the Pathogenesis of Staphylococcus aureus Osteomyelitis

[Image: see text] We used a murine model of postsurgical osteomyelitis (OM) to evaluate the relative virulence of the Staphylococcus aureus strain LAC and five isogenic variants that differ in the functional status of saeRS and sarA relative to each other. LAC and a variant in which saeRS activity i...

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Detalhes bibliográficos
Publicado no:ACS Infect Dis
Main Authors: Ramirez, Aura M., Byrum, Stephanie D., Beenken, Karen E., Washam, Charity, Edmondson, Rick D., Mackintosh, Samuel G., Spencer, Horace J., Tackett, Alan J., Smeltzer, Mark S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294808/
https://ncbi.nlm.nih.gov/pubmed/31722523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.9b00291
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