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Non-homologous end joining: emerging themes and unanswered questions

Non-homologous end joining (NHEJ) is the major pathway for the repair of ionizing radiation induced DNA double strand breaks in human cells. Here, we discuss current insights into the mechanism of NHEJ and the interplay between NHEJ and other pathways for repair of IR-induced DNA damage.

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Detalles Bibliográficos
Main Authors: Radhakrishnan, Sarvan Kumar, Jette, Nicholas, Lees-Miller, Susan P.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084493/
https://ncbi.nlm.nih.gov/pubmed/24582502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2014.01.009
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