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A Trio-Rac1-PAK1 signaling axis drives invadopodia disassembly
Rho family GTPases control cell migration and participate in the regulation of cancer metastasis. Invadopodia, associated with invasive tumor cells, are crucial for cellular invasion and metastasis. To study Rac1 GTPase in invadopodia dynamics, we developed a genetically-encoded, single-chain Rac1 F...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4083618/ https://ncbi.nlm.nih.gov/pubmed/24859002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2972 |
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