A Trio-Rac1-PAK1 signaling axis drives invadopodia disassembly

Rho family GTPases control cell migration and participate in the regulation of cancer metastasis. Invadopodia, associated with invasive tumor cells, are crucial for cellular invasion and metastasis. To study Rac1 GTPase in invadopodia dynamics, we developed a genetically-encoded, single-chain Rac1 F...

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Bibliographic Details
Main Authors: Moshfegh, Yasmin, Bravo-Cordero, Jose Javier, Miskolci, Veronika, Condeelis, John, Hodgson, Louis
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4083618/
https://ncbi.nlm.nih.gov/pubmed/24859002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2972
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