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Actin cytoskeleton reorganization by the tyrosine kinase Syk regulates Fcγ receptor responsiveness by increasing its lateral mobility and clustering

Clustering of immunoreceptors upon association with multivalent ligands triggers important responses including phagocytosis, secretion of cytokines and production of immunoglobulins. We applied single-molecule detection and tracking methods to study the factors that control the mobility and clusteri...

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Autori principali: Jaumouillé, Valentin, Farkash, Yoav, Jaqaman, Khuloud, Das, Raibatak, Lowell, Clifford A., Grinstein, Sergio
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4083245/
https://ncbi.nlm.nih.gov/pubmed/24914558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.04.031
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