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Actin cytoskeleton reorganization by the tyrosine kinase Syk regulates Fcγ receptor responsiveness by increasing its lateral mobility and clustering

Clustering of immunoreceptors upon association with multivalent ligands triggers important responses including phagocytosis, secretion of cytokines and production of immunoglobulins. We applied single-molecule detection and tracking methods to study the factors that control the mobility and clusteri...

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Detalhes bibliográficos
Main Authors: Jaumouillé, Valentin, Farkash, Yoav, Jaqaman, Khuloud, Das, Raibatak, Lowell, Clifford A., Grinstein, Sergio
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4083245/
https://ncbi.nlm.nih.gov/pubmed/24914558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.04.031
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