The Syk Protein Tyrosine Kinase Is Essential for Fcγ Receptor Signaling in Macrophages and Neutrophils

The cytoplasmic protein tyrosine kinase Syk has two amino-terminal SH2 domains that engage phosphorylated immunoreceptor tyrosine-based activation motifs in the signaling subunits of immunoreceptors. Syk, in conjunction with Src family kinases, has been implicated in immunoreceptor signaling in both...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Kiefer, Friedemann, Brumell, John, Al-Alawi, Nadia, Latour, Sylvain, Cheng, Alec, Veillette, André, Grinstein, Sergio, Pawson, Tony
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1998
Assuntos:	Transcriptional Regulation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109005/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9632805/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.7.4209
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