The Syk Protein Tyrosine Kinase Is Essential for Fcγ Receptor Signaling in Macrophages and Neutrophils

The cytoplasmic protein tyrosine kinase Syk has two amino-terminal SH2 domains that engage phosphorylated immunoreceptor tyrosine-based activation motifs in the signaling subunits of immunoreceptors. Syk, in conjunction with Src family kinases, has been implicated in immunoreceptor signaling in both...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Kiefer, Friedemann, Brumell, John, Al-Alawi, Nadia, Latour, Sylvain, Cheng, Alec, Veillette, André, Grinstein, Sergio, Pawson, Tony
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1998
Sujets:	Transcriptional Regulation
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109005/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9632805/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.7.4209
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