All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis

The current study investigates the cellular events which trigger activation of proapoptotic Bcl-2-associated X protein (Bax) in retinal cell death induced by all-trans-retinal (atRAL). Cellular events which activate Bax, such as DNA damage by oxidative stress and phosphorylation of p53, were evaluat...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Sawada, Osamu, Perusek, Lindsay, Kohno, Hideo, Howell, Scott J., Maeda, Akiko, Matsuyama, Shigemi, Maeda, Tadao
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4083191/
https://ncbi.nlm.nih.gov/pubmed/24726920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2014.04.003
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk