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CCL3 production by microglial cells modulates disease severity in murine models of retinal degeneration

Many degenerative retinal diseases illustrate retinal inflammatory changes that include infiltration of microglia and macrophages into the subretinal space. In the current study, we examined the role of chemokines in the Abca4(-/-)Rdh8(-/-) mouse model of Stargardt disease and the Mertk(-/-) mouse m...

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Bibliographic Details
Main Authors: Kohno, Hideo, Maeda, Tadao, Perusek, Lindsay, Pearlman, Eric, Maeda, Akiko
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123815/
https://ncbi.nlm.nih.gov/pubmed/24639355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301738
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