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CCL3 production by microglial cells modulates disease severity in murine models of retinal degeneration

Many degenerative retinal diseases illustrate retinal inflammatory changes that include infiltration of microglia and macrophages into the subretinal space. In the current study, we examined the role of chemokines in the Abca4(-/-)Rdh8(-/-) mouse model of Stargardt disease and the Mertk(-/-) mouse m...

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Detalhes bibliográficos
Main Authors: Kohno, Hideo, Maeda, Tadao, Perusek, Lindsay, Pearlman, Eric, Maeda, Akiko
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123815/
https://ncbi.nlm.nih.gov/pubmed/24639355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301738
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