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CCL3 production by microglial cells modulates disease severity in murine models of retinal degeneration

Many degenerative retinal diseases illustrate retinal inflammatory changes that include infiltration of microglia and macrophages into the subretinal space. In the current study, we examined the role of chemokines in the Abca4(-/-)Rdh8(-/-) mouse model of Stargardt disease and the Mertk(-/-) mouse m...

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Hlavní autoři: Kohno, Hideo, Maeda, Tadao, Perusek, Lindsay, Pearlman, Eric, Maeda, Akiko
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123815/
https://ncbi.nlm.nih.gov/pubmed/24639355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301738
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