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All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis
The current study investigates the cellular events which trigger activation of proapoptotic Bcl-2-associated X protein (Bax) in retinal cell death induced by all-trans-retinal (atRAL). Cellular events which activate Bax, such as DNA damage by oxidative stress and phosphorylation of p53, were evaluat...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4083191/ https://ncbi.nlm.nih.gov/pubmed/24726920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2014.04.003 |
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