Analysis of single-nucleotide polymorphisms (SNPs) in human CYP3A4 and CYP3A5 genes: potential implications for the metabolism of HIV drugs

BACKGROUND: Drug metabolism via the cytochrome P450 (CYP450) system has emerged as an important determinant in the occurrence of several drug interactions (adverse drug reactions, reduced pharmacological effect, drug toxicities). In particular, CYP3A4 and CYP3A5 (interacting with more than 60% of li...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Berno, Giulia, Zaccarelli, Mauro, Gori, Caterina, Tempestilli, Massimo, Antinori, Andrea, Perno, Carlo Federico, Pucillo, Leopoldo Paolo, D’Arrigo, Roberta
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Technical Advance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4083125/
https://ncbi.nlm.nih.gov/pubmed/24986243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-15-76
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados