A carregar...

Low incidence of off-target mutations in individual CRISPR-Cas9 and TALEN targeted human stem cell clones detected by whole-genome sequencing

Genome editing has attracted wide interest for the generation of cellular models of disease using human pluripotent stem cells and other cell types. CRISPR-Cas systems and TALENs can target desired genomic sites with high efficiency in human cells, but recent publications have led to concern about t...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Veres, Adrian, Gosis, Bridget S., Ding, Qiurong, Collins, Ryan, Ragavendran, Ashok, Brand, Harrison, Erdin, Serkan, Talkowski, Michael E., Musunuru, Kiran
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082799/
https://ncbi.nlm.nih.gov/pubmed/24996167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2014.04.020
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!