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Themis2 Is Not Required for B Cell Development, Activation, and Antibody Responses
Themis1 is a protein implicated in transducing signals from the TCR. Mice deficient in Themis1 show a strong impairment in T cell selection in the thymus and defective T cell activation. The related Themis2 protein is expressed in B cells where it associates with signaling proteins Grb2 and Vav1, an...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
AAI
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4082722/ https://ncbi.nlm.nih.gov/pubmed/24907343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400943 |
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