The Transcription Factor E4BP4 Is Not Required for Extramedullary Pathways of NK Cell Development

NK cells contribute to antitumor and antiviral immunosurveillance. Their development in the bone marrow (BM) requires the transcription factor E4BP4/NFIL3, but requirements in other organs are less well defined. In this study, we show that CD3(−)NK1.1(+)NKp46(+)CD122(+) NK cells of immature phenotyp...

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Detalhes bibliográficos
Main Authors: Crotta, Stefania, Gkioka, Annita, Male, Victoria, Duarte, João H., Davidson, Sophia, Nisoli, Ilaria, Brady, Hugh J. M., Wack, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2014
Assuntos:
Immune System Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948112/
https://ncbi.nlm.nih.gov/pubmed/24534532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302765
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