The Transcription Factor E4BP4 Is Not Required for Extramedullary Pathways of NK Cell Development

NK cells contribute to antitumor and antiviral immunosurveillance. Their development in the bone marrow (BM) requires the transcription factor E4BP4/NFIL3, but requirements in other organs are less well defined. In this study, we show that CD3(−)NK1.1(+)NKp46(+)CD122(+) NK cells of immature phenotyp...

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Bibliographic Details
Main Authors: Crotta, Stefania, Gkioka, Annita, Male, Victoria, Duarte, João H., Davidson, Sophia, Nisoli, Ilaria, Brady, Hugh J. M., Wack, Andreas
Format: Artigo
Language:Inglês
Published: AAI 2014
Subjects:
Immune System Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948112/
https://ncbi.nlm.nih.gov/pubmed/24534532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302765
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