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Multiple levels of control determine how E4bp4/Nfil3 regulates NK cell development

The transcription factor E4bp4/Nfil3 has been shown to have a critical role in the development of all innate lymphoid cell types including Natural Killer (NK) cells. Here, we show that post-translational modifications (PTMs) of E4bp4 by either SUMOylation or phosphorylation have profound effects on...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Kostrzewski, Tomasz, Borg, Aaron J., Meng, Yiran, Filipovic, Iva, Male, Victoria, Wack, Andreas, DiMaggio, Peter A., Brady, Hugh J.M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5812440/
https://ncbi.nlm.nih.gov/pubmed/29311361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700981
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