Metallothionein III (MT3) is a putative tumor suppressor gene that is frequently inactivated in pediatric acute myeloid leukemia by promoter hypermethylation

BACKGROUND: Acute myeloid leukemia (AML) is the second most common form of leukemia in children. Aberrant DNA methylation patterns are a characteristic feature in various tumors, including AML. Metallothionein III (MT3) is a tumor suppresser reported to show promoter hypermethylated in various cance...

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Hauptverfasser: Tao, Yan-Fang, Xu, Li-Xiao, Lu, Jun, Cao, Lan, Li, Zhi-Heng, Hu, Shao-Yan, Wang, Na-Na, Du, Xiao-Juan, Sun, Li-Chao, Zhao, Wen-Li, Xiao, Pei-Fang, Fang, Fang, Li, Yan-Hong, Li, Gang, Zhao, He, Li, Yi-Ping, Xu, Yun-Yun, Ni, Jian, Wang, Jian, Feng, Xing, Pan, Jian
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082423/
https://ncbi.nlm.nih.gov/pubmed/24962166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-182
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