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The C-terminal domain of p53 recognizes DNA damaged by ionizing radiation.

p53 accumulates after DNA damage and arrests cellular growth. These findings suggest a possible role for p53 in the cellular response to DNA damage. We have previously shown that the C terminus of p53 binds DNA nonspecifically and assembles stable tetramers. In this study, we have utilized purified...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Reed, M, Woelker, B, Wang, P, Wang, Y, Anderson, M E, Tegtmeyer, P
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1995
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC40820/
https://ncbi.nlm.nih.gov/pubmed/7568153
Tagiau: Ychwanegu Tag
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