The C-terminal domain of p53 recognizes DNA damaged by ionizing radiation.

p53 accumulates after DNA damage and arrests cellular growth. These findings suggest a possible role for p53 in the cellular response to DNA damage. We have previously shown that the C terminus of p53 binds DNA nonspecifically and assembles stable tetramers. In this study, we have utilized purified...

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Detaylı Bibliyografya
Asıl Yazarlar: Reed, M, Woelker, B, Wang, P, Wang, Y, Anderson, M E, Tegtmeyer, P
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1995
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC40820/
https://ncbi.nlm.nih.gov/pubmed/7568153
Etiketler: Etiketle
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