Identification of Mixed Lineage Leukemia 1(MLL1) Protein as a Coactivator of Heat Shock Factor 1(HSF1) Protein in Response to Heat Shock Protein 90 (HSP90) Inhibition

Heat shock protein 90 (HSP90) inhibition inhibits cancer cell proliferation through depleting client oncoproteins and shutting down multiple oncogenic pathways. Therefore, it is an attractive strategy for targeting human cancers. Several HSP90 inhibitors, including AUY922 and STA9090, show promising...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Chen, Yaoyu, Chen, Jinyun, Yu, Jianjun, Yang, Guizhi, Temple, Emilia, Harbinski, Fred, Gao, Hui, Wilson, Christopher, Pagliarini, Raymond, Zhou, Wenlai
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Biochemistry and Molecular Biology 2014
الموضوعات:
Gene Regulation
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081932/
https://ncbi.nlm.nih.gov/pubmed/24831003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.574053
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