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The transcriptional coactivator PGC1α protects against hyperthermic stress via cooperation with the heat shock factor HSF1
Heat shock proteins (HSPs) are required for the clearance of damaged and aggregated proteins and have important roles in protein homeostasis. It has been shown that the heat shock transcription factor, HSF1, orchestrates the transcriptional induction of these stress-regulated chaperones; however, th...
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| Publicado no: | Cell Death Dis |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5399192/ https://ncbi.nlm.nih.gov/pubmed/26890141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.22 |
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