The transcriptional coactivator PGC1α protects against hyperthermic stress via cooperation with the heat shock factor HSF1

Heat shock proteins (HSPs) are required for the clearance of damaged and aggregated proteins and have important roles in protein homeostasis. It has been shown that the heat shock transcription factor, HSF1, orchestrates the transcriptional induction of these stress-regulated chaperones; however, th...

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Bibliographic Details
Published in:Cell Death Dis
Main Authors: Xu, L, Ma, X, Bagattin, A, Mueller, E
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399192/
https://ncbi.nlm.nih.gov/pubmed/26890141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.22
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