Adoptively transferred melanoma-reactive CTL primed in the presence of IL-21 and transferred with concurrent CTLA4 blockade results in enhanced CTL persistence and tumor regression

Lignende værker

• Combined IL-21–primed polyclonal CTL plus CTLA4 blockade controls refractory metastatic melanoma in a patient
  af: Chapuis, Aude G., et al.
  Udgivet: (2016)
• T-Cell Therapy Using Interleukin-21–Primed Cytotoxic T-Cell Lymphocytes Combined With Cytotoxic T-Cell Lymphocyte Antigen-4 Blockade Results in Long-Term Cell Persistence and Durable Tumor Regression
  af: Chapuis, Aude G., et al.
  Udgivet: (2016)
• CTLA-4 blockade plus adoptive T cell transfer promotes optimal melanoma immunity in mice
  af: Mahvi, David A., et al.
  Udgivet: (2015)
• Tracking the Fate and Origin of Clinically Relevant Adoptively Transferred CD8(+) T Cells In Vivo
  af: Chapuis, Aude G, et al.
  Udgivet: (2017)
• Transferred melanoma-specific CD8(+) T cells persist, mediate tumor regression, and acquire central memory phenotype
  af: Chapuis, Aude G., et al.
  Udgivet: (2012)