Transferred melanoma-specific CD8(+) T cells persist, mediate tumor regression, and acquire central memory phenotype

Eitemau Tebyg

• Adoptively transferred melanoma-reactive CTL primed in the presence of IL-21 and transferred with concurrent CTLA4 blockade results in enhanced CTL persistence and tumor regression
  gan: Yee, Cassian, et al.
  Cyhoeddwyd: (2014)
• T-Cell Therapy Using Interleukin-21–Primed Cytotoxic T-Cell Lymphocytes Combined With Cytotoxic T-Cell Lymphocyte Antigen-4 Blockade Results in Long-Term Cell Persistence and Durable Tumor Regression
  gan: Chapuis, Aude G., et al.
  Cyhoeddwyd: (2016)
• Combined IL-21–primed polyclonal CTL plus CTLA4 blockade controls refractory metastatic melanoma in a patient
  gan: Chapuis, Aude G., et al.
  Cyhoeddwyd: (2016)
• Fludarabine Modulates Immune Response and Extends In Vivo Survival of Adoptively Transferred CD8 T Cells in Patients with Metastatic Melanoma
  gan: Wallen, Herschel, et al.
  Cyhoeddwyd: (2009)
• Regression of metastatic Merkel cell carcinoma following transfer of polyomavirus-specific T cells and therapies capable of re-inducing HLA class-I
  gan: Chapuis, Aude G., et al.
  Cyhoeddwyd: (2013)