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Transferred melanoma-specific CD8(+) T cells persist, mediate tumor regression, and acquire central memory phenotype
Adoptively transferred tumor-specific T cells offer the potential for non–cross-resistant therapy and long-term immunoprotection. Strategies to enhance in vivo persistence of transferred T cells can lead to improved antitumor efficacy. However, the extrinsic (patient conditioning) and intrinsic (eff...
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Main Authors: | , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3311364/ https://ncbi.nlm.nih.gov/pubmed/22393002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113748109 |
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