FBXW7 Mutations in Melanoma and a New Therapeutic Paradigm

BACKGROUND: Melanoma is a heterogeneous tumor with subgroups requiring distinct therapeutic strategies. Genetic dissection of melanoma subgroups and identification of therapeutic agents are of great interest in the field. These efforts will ultimately lead to treatment strategies, likely combinatori...

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Main Authors: Aydin, Iraz T., Melamed, Rachel D., Adams, Sarah J., Castillo-Martin, Mireia, Demir, Ahu, Bryk, Diana, Brunner, Georg, Cordon-Cardo, Carlos, Osman, Iman, Rabadan, Raul, Celebi, Julide Tok
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081626/
https://ncbi.nlm.nih.gov/pubmed/24838835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/dju107
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