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Detection and characterization of spacer integration intermediates in type I-E CRISPR–Cas system

The adaptation against foreign nucleic acids by the CRISPR–Cas system (Clustered Regularly Interspaced Short Palindromic Repeats and CRISPR-associated proteins) depends on the insertion of foreign nucleic acid-derived sequences into the CRISPR array as novel spacers by still unknown mechanism. We id...

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Detalhes bibliográficos
Main Authors: Arslan, Zihni, Hermanns, Veronica, Wurm, Reinhild, Wagner, Rolf, Pul, Ümit
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081107/
https://ncbi.nlm.nih.gov/pubmed/24920831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku510
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