Cas4 Nucleases Can Effect Specific Integration of CRISPR Spacers

Clustered regularly interspaced short palindromic repeat (CRISPR)-Cas systems incorporate short DNA fragments from invasive genetic elements into host CRISPR arrays in order to generate host immunity. Recently, we demonstrated that the Csa3a regulator protein triggers CCN protospacer-adjacent motif...

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Bibliographic Details
Published in:J Bacteriol
Main Authors: Zhang, Zhufeng, Pan, Saifu, Liu, Tao, Li, Yingjun, Peng, Nan
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6531622/
https://ncbi.nlm.nih.gov/pubmed/30936372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00747-18
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