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CANOES: detecting rare copy number variants from whole exome sequencing data

We present CANOES, an algorithm for the detection of rare copy number variants from exome sequencing data. CANOES models read counts using a negative binomial distribution and estimates variance of the read counts using a regression-based approach based on selected reference samples in a given datas...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Backenroth, Daniel, Homsy, Jason, Murillo, Laura R., Glessner, Joe, Lin, Edwin, Brueckner, Martina, Lifton, Richard, Goldmuntz, Elizabeth, Chung, Wendy K., Shen, Yufeng
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081054/
https://ncbi.nlm.nih.gov/pubmed/24771342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku345
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