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CANOES: detecting rare copy number variants from whole exome sequencing data

We present CANOES, an algorithm for the detection of rare copy number variants from exome sequencing data. CANOES models read counts using a negative binomial distribution and estimates variance of the read counts using a regression-based approach based on selected reference samples in a given datas...

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Sonraí Bibleagrafaíochta
Main Authors: Backenroth, Daniel, Homsy, Jason, Murillo, Laura R., Glessner, Joe, Lin, Edwin, Brueckner, Martina, Lifton, Richard, Goldmuntz, Elizabeth, Chung, Wendy K., Shen, Yufeng
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081054/
https://ncbi.nlm.nih.gov/pubmed/24771342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku345
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