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Sulfated, Low Molecular Weight Lignins are Potent Inhibitors of Plasmin, in Addition to Thrombin and Factor Xa : Novel Opportunity for Controlling Complex Pathologies

Recently we prepared sulfated, low molecular weight lignins (LMWLs) to mimic the biological activities of heparin and heparan sulfate. Chemo-enzymatically prepared sulfated LMWLs represent a library of diverse non-sugar, aromatic molecules with structures radically different from the heparins, and h...

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Detalhes bibliográficos
Main Authors: Henry, Brian L., Abdel Aziz, May, Zhou, Qibing, Desai, Umesh R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080834/
https://ncbi.nlm.nih.gov/pubmed/20024500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH09-07-0454
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