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Dynamic affinity chromatography in the separation of sulfated lignins binding to thrombin

Sulfated low molecular weight lignins (LMWLs), a mixture of chemo-enzymatically prepared oligomers, have been found to be potent antagonists of coagulation. However, structures that induce anticoagulation remain unidentified. The highly polar sulfate groups on these molecules and the thousands of di...

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Bibliographic Details
Main Authors: Liang, Aiye, Thakkar, Jay N., Hindle, Michael, Desai, Umesh R.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4099362/
https://ncbi.nlm.nih.gov/pubmed/23122400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2012.09.036
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