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Identification of the site of binding of sulfated, low molecular weight lignins on thrombin

Sulfated, low molecular weight lignins (LMWLs), designed recently as macromolecular mimetics of the low molecular weight heparins (LMWHs), were found to exhibit a novel allosteric mechanism of inhibition of human thrombin, factor Xa and plasmin, which translates into potent human blood anticoagulati...

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Détails bibliographiques
Auteurs principaux: Abdel Aziz, May H., Mosier, Philip D., Desai, Umesh R.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183121/
https://ncbi.nlm.nih.gov/pubmed/21893043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.08.102
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