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Identification of the site of binding of sulfated, low molecular weight lignins on thrombin
Sulfated, low molecular weight lignins (LMWLs), designed recently as macromolecular mimetics of the low molecular weight heparins (LMWHs), were found to exhibit a novel allosteric mechanism of inhibition of human thrombin, factor Xa and plasmin, which translates into potent human blood anticoagulati...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3183121/ https://ncbi.nlm.nih.gov/pubmed/21893043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.08.102 |
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