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Antibody-Mediated Graft Injury: Complement-Dependent and Complement-Independent Mechanisms

PURPOSE OF REVIEW: Antibody-mediated rejection (AMR) is emerging as the leading cause of chronic rejection and allograft failure. Traditionally, the mechanisms of graft injury mediated by donor specific antibodies beyond complement activation were not well appreciated. However, an evolving paradigm...

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Autori principali: Valenzuela, Nicole M, McNamara, Jeffrey T, Reed, Elaine F
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080796/
https://ncbi.nlm.nih.gov/pubmed/24316758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOT.0000000000000040
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