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Antibody-Mediated Graft Injury: Complement-Dependent and Complement-Independent Mechanisms

PURPOSE OF REVIEW: Antibody-mediated rejection (AMR) is emerging as the leading cause of chronic rejection and allograft failure. Traditionally, the mechanisms of graft injury mediated by donor specific antibodies beyond complement activation were not well appreciated. However, an evolving paradigm...

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Bibliographic Details
Main Authors: Valenzuela, Nicole M, McNamara, Jeffrey T, Reed, Elaine F
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080796/
https://ncbi.nlm.nih.gov/pubmed/24316758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOT.0000000000000040
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