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Antibody-Mediated Graft Injury: Complement-Dependent and Complement-Independent Mechanisms

PURPOSE OF REVIEW: Antibody-mediated rejection (AMR) is emerging as the leading cause of chronic rejection and allograft failure. Traditionally, the mechanisms of graft injury mediated by donor specific antibodies beyond complement activation were not well appreciated. However, an evolving paradigm...

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Detalhes bibliográficos
Main Authors: Valenzuela, Nicole M, McNamara, Jeffrey T, Reed, Elaine F
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080796/
https://ncbi.nlm.nih.gov/pubmed/24316758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOT.0000000000000040
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