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In Search of Antiaging Modalities: Evaluation of mTOR- and ROS/DNA Damage-Signaling by Cytometry
This review presents the evidence in support of the IGF-1/mTOR/S6K1 signaling as the primary factor contributing to aging and cellular senescence. Reviewed are also specific interactions between mTOR/S6K1 and ROS-DNA damage signaling pathways. Outlined are critical sites along these pathways, includ...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4080725/ https://ncbi.nlm.nih.gov/pubmed/24677687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cyto.a.22452 |
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