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Antioxidant Enzymes Reduce DNA Damage and Early Activation of Valvular Interstitial Cells in Aortic Valve Sclerosis

OBJECTIVE: Accumulation of reactive oxygen species (ROS) and remodeling of the microstructure of the cusp characterize aortic valve sclerosis, the early phase of calcific aortic valve disease. These events are associated with activation of valvular interstitial cells (VICs) toward an osteogenic-like...

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書誌詳細
主要な著者: Branchetti, Emanuela, Sainger, Rachana, Poggio, Paolo, Grau, Juan B., Patterson-Fortin, Jeffrey, Bavaria, Joseph E., Chorny, Michael, Lai, Eric, Gorman, Robert C., Levy, Robert J., Ferrari, Giovanni
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080420/
https://ncbi.nlm.nih.gov/pubmed/23241403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.300177
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