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Dephosphorylation of circulating human Osteopontin correlates with severe valvular calcification in patients with Calcific Aortic Valve Disease

CONTEXT: Calcific Aortic Valve Disease (CAVD) is an active pathological process leading to biomineralization of the aortic cusps. We characterized circulating and tissue Osteopontin (OPN) as a biomarker for CAVD. OBJECTIVES: Here we investigate the post-translational modifications of circulating OPN...

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Detalhes bibliográficos
Main Authors: Sainger, Rachana, Grau, Juan B., Poggio, Paolo, Branchetti, Emanuela, Bavaria, Joseph E., Gorman, Joseph H., Gorman, Robert C., Ferrari, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3291739/
https://ncbi.nlm.nih.gov/pubmed/22191734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/1354750X.2011.642407
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