LaSSO, a strategy for genome-wide mapping of intronic lariats and branch points using RNA-seq

Both canonical and alternative splicing of RNAs are governed by intronic sequence elements and produce transient lariat structures fastened by branch points within introns. To map precisely the location of branch points on a genomic scale, we developed LaSSO (Lariat Sequence Site Origin), a data-dri...

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Detalles Bibliográficos
Main Authors: Bitton, Danny A., Rallis, Charalampos, Jeffares, Daniel C., Smith, Graeme C., Chen, Yuan Y.C., Codlin, Sandra, Marguerat, Samuel, Bähler, Jürg
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2014
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Method
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079972/
https://ncbi.nlm.nih.gov/pubmed/24709818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.166819.113
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