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LaSSO, a strategy for genome-wide mapping of intronic lariats and branch points using RNA-seq

Both canonical and alternative splicing of RNAs are governed by intronic sequence elements and produce transient lariat structures fastened by branch points within introns. To map precisely the location of branch points on a genomic scale, we developed LaSSO (Lariat Sequence Site Origin), a data-dri...

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Hlavní autoři: Bitton, Danny A., Rallis, Charalampos, Jeffares, Daniel C., Smith, Graeme C., Chen, Yuan Y.C., Codlin, Sandra, Marguerat, Samuel, Bähler, Jürg
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079972/
https://ncbi.nlm.nih.gov/pubmed/24709818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.166819.113
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