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LaSSO, a strategy for genome-wide mapping of intronic lariats and branch points using RNA-seq

Both canonical and alternative splicing of RNAs are governed by intronic sequence elements and produce transient lariat structures fastened by branch points within introns. To map precisely the location of branch points on a genomic scale, we developed LaSSO (Lariat Sequence Site Origin), a data-dri...

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Dettagli Bibliografici
Autori principali: Bitton, Danny A., Rallis, Charalampos, Jeffares, Daniel C., Smith, Graeme C., Chen, Yuan Y.C., Codlin, Sandra, Marguerat, Samuel, Bähler, Jürg
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079972/
https://ncbi.nlm.nih.gov/pubmed/24709818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.166819.113
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