Widespread exon skipping triggers degradation by nuclear RNA surveillance in fission yeast

Exon skipping is considered a principal mechanism by which eukaryotic cells expand their transcriptome and proteome repertoires, creating different splice variants with distinct cellular functions. Here we analyze RNA-seq data from 116 transcriptomes in fission yeast (Schizosaccharomyces pombe), cov...

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Vydáno v:Genome Res
Hlavní autoři: Bitton, Danny A., Atkinson, Sophie R., Rallis, Charalampos, Smith, Graeme C., Ellis, David A., Chen, Yuan Y.C., Malecki, Michal, Codlin, Sandra, Lemay, Jean-François, Cotobal, Cristina, Bachand, François, Marguerat, Samuel, Mata, Juan, Bähler, Jürg
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448684/
https://ncbi.nlm.nih.gov/pubmed/25883323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.185371.114
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