Hypoxia lowers SLC30A8/ZnT8 expression and free cytosolic Zn(2+) in pancreatic beta cells

AIMS/HYPOTHESIS: Hypoxic damage complicates islet isolation for transplantation and may contribute to beta cell failure in type 2 diabetes. Polymorphisms in the SLC30A8 gene, encoding the secretory granule zinc transporter 8 (ZnT8), influence type 2 diabetes risk, conceivably by modulating cytosolic...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Gerber, Philipp A., Bellomo, Elisa A., Hodson, David J., Meur, Gargi, Solomou, Antonia, Mitchell, Ryan K., Hollinshead, Michael, Chimienti, Fabrice, Bosco, Domenico, Hughes, Stephen J., Johnson, Paul R. V., Rutter, Guy A.
格式: Artigo
語言:Inglês
出版: Springer Berlin Heidelberg 2014
主題:
Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079946/
https://ncbi.nlm.nih.gov/pubmed/24865615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-014-3266-0
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍